Anne-Marie : President and Founder of A-M B-Well Inc REFER A FRIEND PROMO!!!

A spooky October greeting to all of my valued Customers, Case Club Members and Friends receiving this edition of our monthly newsletter!

A heartfelt thank you to all of those who continue to support A-M B-Well Inc. by providing themselves and their loved ones the benefits of the highest quality pharmaceutical grade fish oil. Remember we have both PGFO Capsules as well as our hugely popular Liquid Gold!!

This month we have found an interesting article on the heart healthy reasons companies are turning to fish oil!

Please enjoy!

The 5 Heart Healthy Reasons Drug Companies are Turning to Fish Oil


October 10, 2013

As a pharmacist I often find myself engaged in lively debate focused on contentious issues most pertinent to this profession. Advocating a nutritional stance I am regularly a lone voice swallowed up in a sea of conventional wisdom. So it was nice to see that on the topic of omega 3 fish oil consumption, of which I have been a staunch defender, I have received unlikely support from Big Pharma. They have been casting their nets for the next big heart cure, and fish oil is the catch of the day. Following their public endorsement of this often derided supplement analysts now suggest that as many as one third of adults will be prescribed fish oils by their doctors in the next few years. The question is though, what are the benefits that caused this change in heart about fish oils?

Inhibit Inflammation

It’s an often overlooked factor in heart disease, and mistakenly so – inflammation is the underlying driver of arteriosclerosis. The earliest stage of plaque formation occurs when inflammatory factors (called macrophages and T-lymphocytes) infiltrate the injured arterial wall endothelium, forming fatty streaks. In addition to this, the injured endothelium releases its own inflammation promoting factors, only to exacerbate matters.

It is the pro-inflammatory effects of insulin that largely explains why high sugar consumption is so bad for our hearts, and the inflammatory chemicals released by fat tissue that predisposes overweight individuals to developing cardiovascular and metabolic disease.

A simple blood test of one of the most common inflammation measurements – called C reactive protein – is especially effective in predicting one’s risk of heart disease.

Fish oils massively dampen overall inflammation in the body. They reduce the synthesis of highly inflammatory members of what’s called the eicosanoid family, as well as promoting the production of newly discovered classes of potent anti-inflammatory mediators called resolvins and protectins.

Arrest Aggregation

Platelet aggregation is key in clot formation, and with it comes a dramatically increased risk of heart attack and stroke. Fish oils exert anti-platelet effects through multiple mechanisms, the primary means; a reduction in ADP induced platelet aggregation. As well as being effective in their own right, they also enhance the effects of conventional anti-platelet drug therapy.

The sex of the patient introduces an interesting consideration when selecting fish oils for their anti-platelet effects. A recent study found that men are only responsive to the omega 3 constituent EPA, not DHA, while the inverse is true for women, DHA responsive, EPA unresponsive.

Better Blood Pressure

When fish oils are consumed at doses of 3 grams omega 3 a day or more they exert a blood pressure lowering effect. The magnitude of the effect appears determined by the starting blood pressure and age of the patient, with maximal benefit achieved in hypertensive patients aged over 45 years.

On top of this fish oils consumption lowers heart rate in those with higher heart rates to begin with (resting heart rate > 70bpm) – confirming that fish oils effect the electrophysiology of the heart. Some researchers have suggested that it is only the DHA component of fish oil which exerts this effect.

Enhanced Endothelial Function

Endothelial dysfunction of the arterial wall is a key event in the development of atherosclerosis. In older individuals and those already presenting with cardiovascular risk factors, fish oil consumption relaxes and increases the diameter of blood vessels, improving blood flow and reducing the chances of damage occurring to the artery walls.

Lower Lipids

Non-HDL-Cholesterol is widely considered the most accurate predictor of cardiovascular disease, accounting for both LDL cholesterol and VLDL cholesterol (triglycerides) – each of which is harmful. Whereas statins lower non-HDL cholesterol predominantly through lowering LDL, fish oils do so by reducing VLDL/ triglycerides. They do this through a threefold action on the liver; acting as poor substrates for triglyceride synthesis, directly inhibit triglyceride synthesis, and promoting ‘burning’ of fats making them unavailable for making triglycerides.

In one of the most recent trials of fish oils in statin treated patients, 2 grams of a highly concentrated, bioavailable fish oil product reduced non-HDL cholesterol by 4%. Whilst, at first glance, 4% may not appear a change of significant magnitude, it is worth noting that this is equivalent to what would be seen if the patient doubled their statin dose (exposing them to all the side effects that come with such increases). Upping the dose to 4 grams reduced non-HDL cholesterol 7%, the same effect as trebling the statin dose.


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Omega-3 PGFO capsules and Omega-3 Liquid Gold are identical in price, being $25.75 per bottle. Below is a chart listing the prices on the Order Page for Canada and U.S. Retail. The price shows the total price for 1 to 11 bottles with the freight included, then breaks it down by the price per bottle. 8 to 11 bottles are shipped freight-free.

The second chart called Case Club Membership lists the prices on the Order Page for Canada and U.S. Wholesale. This chart is to show you how much money you can save per bottle if you order by the case (12 bottles) and also join the Case Club. You will further note that the second chart also shows the total price for bottles for 12, 24 and 36 bottles based on Regular and Case Club prices, then breaks it down by the price per bottle. As you can see, you are paying considerably less per bottle by ordering in bulk.


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